Movie S2. Sustained T cell–CD11c+ cell interactions in a lightly infiltrated islet. Movie of the data represented in Fig. 2A. CD2-dsRed.OT-I CD8+ T cells were transferred into RIP-mOva.CD11c-YFP recipient mice. Islets were isolated 5 d following T-cell transfer and immobilized in low-melting agarose. Isolated islets were imaged by time-lapse two-photon microscopy. Representative time-lapse imaging of sustained T-cell interactions in a lightly infiltrated islet. Movie represents an area of 90 μm (x) × 90 μm (y) × 15 μm (z). Time stamp, min:sec.