Video 4

Movie S4. Sustained T cell–CD11c+ cell interactions leading to APC killing in a lightly infiltrated islet. Movie of the data represented in Fig. 4B. CD2-dsRed.OT-I T cells were transferred into RIP-mOva.CD11c-YFP recipients. Isolated islets were imaged by time-lapse two-photon microscopy. Representative time-lapse imaging of sustained T-cell interactions leading to CD11c+ cell killing in a lightly infiltrated islet. Movie represents 105 μm (x) × 105 μm (y) × 15 μm (z). Time stamp, min:sec.