Video 3
Movie S3. Tubulation of MT1-MMP–mCherry–containing vesicles in dyn-2–depleted cells. MDA-MB-231 cells overexpressing MT1-MMP–mCherry were treated with siRNAs against PKCζ/ι, plated on gelatin, and imaged by confocal spinning-disk microscopy. Images were taken every 2 s. (Scale bar: 5 μm.)
Control of MT1-MMP transport by atypical PKC during breast-cancer progression
PNAS. 2014. 111:E1872-E1879 DOI: 10.1073/pnas.1400749111