Video 8

Movie S8. RapR Src activation in cells with disrupted microtubules induced randomized protrusion. COS-7 cells cotransfected with RapR Src-EGFP and mCherry-FRB were imaged before and after addition of rapamycin. Nocodazole was added 30 min before kinase activation. GFP images were taken every 2 min.

Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms

Pei-Hsuan Chu, Denis Tsygankov, Matthew E. Berginski, Onur Dagliyan, Shawn M. Gomez, Timothy C. Elston, Andrei V. Karginov, and Klaus M. Hahn

PNAS. 2014. 111:12420-12425 DOI: 10.1073/pnas.1404487111