Video 8

Movie S8. NPCs express myelin proteolipid protein (PLP) and wrap around damaged axons. PLP-GFP-NPCs (green) and Thy1-YFP+ axons (yellow) are visualized under 2P excitation 2 wk following transplant into a JHMV-infected Thy1-YFP spinal cord. PLP-GFP wrapping is highlighted in red. Movie duration = 36:11 (min:s). (Scale bar, 10–5 μm.)

Two-photon imaging of remyelination of spinal cord axons by engrafted neural precursor cells in a viral model of multiple sclerosis

Milton L. Greenberg, Jason G. Weinger, Melanie P. Matheu, Kevin S. Carbajal, Ian Parker, Wendy B. Macklin, Thomas E. Lane, and Michael D. Cahalan

PNAS. 2014. 111:E2349-E2355 DOI: 10.1073/pnas.1406658111