Video 1

Movie S1. E-cad::GFP dynamics during epithelial wound closure. Time-lapse imaging of wound closure in the ventral epidermis of an embryo at stage 15 expressing ubi-E-cad::GFP. Immediately after wounding E-cad::GFP decreases at the membranes of epidermal cells facing the wound. This event is followed by the formation of E-cad::GFP foci in the lateral planes of the wound-edge cells that are clearly seen in this video at 10 min postwounding. Images are the maximum z-projections of an 18-µm stack (49 slices) and were captured every 5 min on an Andor Revolution Spinning Disk Confocal Microscope. The first frame shows the embryo before wounding. (Scale bar: 10 μm.)

The Toll/NF-κB signaling pathway is required for epidermal wound repair in Drosophila

Lara Carvalho, António Jacinto, and Nina Matova

PNAS. 2014. 111:E5373-E5382 DOI: 10.1073/pnas.1408224111