To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie S5. A dynamic region of interest (ROI) is placed near the tip of the actin shaft. The position of the ROI is kept constant in the reference frame of the bead, and hence the same region of the filopodium is being quantified. Helical buckling of actin inside filopodia generates traction Natascha Leijnse, Lene B. Oddershede, and Poul M. Bendix PNAS. 2014. DOI: 10.1073/pnas.1411761112 Download Original Video Browse All Videos »