To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Video 5 Movie S5. Time-lapse movie of a cell with a nascent protrusion on control substrates during microneedle manipulation. Images for the time-lapse movie were captured every minute. Total duration, 9 min. Fibroblasts probe substrate rigidity with filopodia extensions before occupying an area Stephanie Wong, Wei-Hui Guo, and Yu-Li Wang PNAS. 2014. DOI: 10.1073/pnas.1412285111 Download Original Video Browse All Videos »