Video 2

Movie S2. Tubules emerge from maturing latex bead phagosomes hours after phagocytosis in DCs. This movie, corresponding to panels shown in Fig. 1B, illustrates tubule formation from phagosomes in WT DCs pulsed with LPS/OVA-TxR beads and chased for 2.5 h. The time scale in seconds is indicated at the lower left.

TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation

Adriana R. Mantegazza, Allison L. Zajac, Alison Twelvetrees, Erika L. F. Holzbaur, Sebastián Amigorena, and Michael S. Marks

PNAS. 2014. DOI: 10.1073/pnas.1412998111