Video 5

Movie S5. Costimulation of TLR3 with poly(I:C) adhered to LPS beads restores cytokine secretion, but not phagotubule formation, in DCs treated with IRAK-1/4 inhibitor (associated with Fig. S2). The movie shows phagotubule formation (or absence thereof) at 2.5 h after phagocytosis of LPS/OVA-TxR/ poly(I:C) beads by WT BMDCs that were untreated or pretreated with IRAK-1/4 inhibitor or 3-MA as indicated. The time scale in seconds is indicated at the lower left.