Video 7

Movie S7. Phagotubules contain MHC-II molecules. This movie shows two examples of phagotubule formation at 2.5 h after phagocytosis of LPS/OVA-TxR beads (red fluorescence) by BMDCs from WT mice expressing MHC-II-GFP (green fluorescence). The time scale in seconds is indicated at the lower left.

TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation

Adriana R. Mantegazza, Allison L. Zajac, Alison Twelvetrees, Erika L. F. Holzbaur, Sebastián Amigorena, and Michael S. Marks

PNAS. 2014. DOI: 10.1073/pnas.1412998111