Video 2

Movie S2. Spontaneous calcium bursts are suppressed in topotecan-treated cortical neuron cultures. Fura-2 calcium imaging of topotecan-treated (300 nM) cortical neurons in ACSF after the addition of 5 μM GBZ, after the addition of GBZ plus 5 μM DNQX, and after neurons were depolarized with 55 mM KCl.