Movie S1.

Vascular network in Notch4* mutant before AV shunt formation. Three-dimensional rendering of a two-photon imaging stack from the P14 Notch4* mutant shown in Fig. 1A.

Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels

Patrick A. Murphy, Tyson N. Kim, Lawrence Huang, Corinne M. Nielsen, Michael T. Lawton, Ralf H. Adams, Chris B. Schaffer, and Rong A. Wang

PNAS. 2014. DOI: 10.1073/pnas.1415316111