Movie S2.

3D confocal reconstruction of a vascular tree with positive staining for vascular endothelial (VE)-cadherin, demonstrating the presence of adherens junctions. Cell nuclei were stained with DAPI (blue). Adherens junctions appear in red (VE-cadherin).

Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation

Jessie S. Jeon, Simone Bersini, Mara Gilardi, Gabriele Dubini, Joseph L. Charest, Matteo Moretti, and Roger D. Kamm

PNAS. 2014. DOI: 10.1073/pnas.1417115112