Movie S4.

Time-lapse view of cancer cell extravasation. Cancer cells (red) are shown while migrating across the microvessel wall (green) and invading the bone-mimicking matrix. Total movie duration, 8 h; time step, 30 min.

Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation

Jessie S. Jeon, Simone Bersini, Mara Gilardi, Gabriele Dubini, Joseph L. Charest, Matteo Moretti, and Roger D. Kamm

PNAS. 2014. DOI: 10.1073/pnas.1417115112