Video 1

Movie S1. NLRC4 is required for limiting macrophages movement following Salmonella infection. The green area indicates the output of the segmentation software. The red dots correspond to the center of the green areas and are shown accumulating over time. Salmonella-infected WT BMMs (identified by the presence of bacteria within the cell) decrease their motility between 20 and 30 min after inoculation compared with uninfected cells, whereas Nlrc4−/− BMMs retain their ability to move after infection. (Scale bars, 10 μm.)

Actin polymerization as a key innate immune effector mechanism to control Salmonella infection

Si Ming Man, Andrew Ekpenyong, Panagiotis Tourlomousis, Sarra Achouri, Eugenia Cammarota, Katherine Hughes, Alessandro Rizzo, Gilbert Ng, John A. Wright, Pietro Cicuta, Jochen R. Guck, and Clare E. Bryant

PNAS. 2014. DOI: 10.1073/pnas.1419925111