Movie S6B.
Imaging the presence of tumor-associated class II MHC+ cells using 18F-VHH7 (anti-mouse class II MHC). A WT mouse was inoculated s.c. on the left shoulder with mouse B16 melanoma cells and imaged 7 d postinjection. Tumor cells lack mouse class II MHC molecules. Movies and images are representative of two to four mice with similar results.
Noninvasive imaging of immune responses
PNAS. 2015. 112:6146-6151 DOI: 10.1073/pnas.1502609112