Movie S6B.

Imaging the presence of tumor-associated class II MHC+ cells using 18F-VHH7 (anti-mouse class II MHC). A WT mouse was inoculated s.c. on the left shoulder with mouse B16 melanoma cells and imaged 7 d postinjection. Tumor cells lack mouse class II MHC molecules. Movies and images are representative of two to four mice with similar results.

Noninvasive imaging of immune responses

Mohammad Rashidian, Edmund J. Keliher, Angelina M. Bilate, Joao N. Duarte, Gregory R. Wojtkiewicz, Johanne Tracey Jacobsen, Juanjo Cragnolini, Lee Kim Swee, Gabriel D. Victora, Ralph Weissleder, and Hidde L. Ploegh

PNAS. 2015. 112:6146-6151 DOI: 10.1073/pnas.1502609112