Movie S1.

Animated structure of full-length IFP created by PyMol. The PAS and GAF domains are shown in cyan and yellow, respectively. The catalytic cysteine and the chromophore (BV) are shown in red and purple, respectively. The protein has a diameter of about 5 nm.

Rationally designed fluorogenic protease reporter visualizes spatiotemporal dynamics of apoptosis in vivo

Tsz-Leung To, Beverly J. Piggott, Kalpana Makhijani, Dan Yu, Yuh Nung Jan, and Xiaokun Shu

PNAS. 2015. 112:3338-3343 DOI: 10.1073/pnas.1502857112