To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie S1. Enumeration of carbocationic intermediates in the active site of B5GLM7. Computational-guided discovery and characterization of a sesquiterpene synthase from Streptomyces clavuligerus Jeng-Yeong Chow, Bo-Xue Tian, Gurusankar Ramamoorthy, Brandan S. Hillerich, Ronald D. Seidel, Steven C. Almo, Matthew P. Jacobson, and C. Dale Poulter PNAS. 2015. DOI: 10.1073/pnas.1505127112 Download Original Video Browse All Videos »