Movie S12.

Migration of LAT-GFP–expressing OT-I CD8+ T cells in Kb-Q4–coated microchannels, showing changes in LAT polarity and punctuated LAT accumulations. Images were acquired every 3 min.

Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrest

Hélène D. Moreau, Fabrice Lemaître, Kym R. Garrod, Zacarias Garcia, Ana-Maria Lennon-Duménil, and Philippe Bousso

PNAS. 2015. 112:12151-12156 DOI: 10.1073/pnas.1506654112

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