Movie S2.

Electron density and structure of the mouse ASC-PYD filament. Density and structural models for a single ASC-PYD monomer are shown in the same representation as in Movie S1. Residues E34, Q31, Q79 and Y59 are shown in side-chain representation (in order of appearance). Note the improved fitting of model 3 (blue) to the electron density compared with model 1 (beige).