Movie S3.

Structure of the mouse ASC-PYD filament. Top and side views of a rotating 15-subunit segment of the ASC-PYD filament are shown in surface representation. The three helical oligomer strands are colored blue, teal, and dark blue, and individual ASC-PYD units within each strand are reported with alternating darker and lighter shades.

Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy

Lorenzo Sborgi, Francesco Ravotti, Venkata P. Dandey, Mathias S. Dick, Adam Mazur, Sina Reckel, Mohamed Chami, Sebastian Scherer, Matthias Huber, Anja Böckmann, Edward H. Egelman, Henning Stahlberg, Petr Broz, Beat H. Meier, and Sebastian Hiller

PNAS. 2015. DOI: 10.1073/pnas.1507579112