Movie S1.

Live engineered hPSC-CM. This cell was imaged by bright-field microscopy; its nucleus was labeled with Hoechst. The cell contracts along the pattern major axis.

Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness

Alexandre J. S. Ribeiro, Yen-Sin Ang, Ji-Dong Fu, Renee N. Rivas, Tamer M. A. Mohamed, Gadryn C. Higgs, Deepak Srivastava, and Beth L. Pruitt

PNAS. 2015. 112:12705-12710 DOI: 10.1073/pnas.1508073112