MIMIR in an old mouse with experimental glaucoma 3 d after laser treatment shows less transport of mitochondria in the RGC axons (asterisks) than in adult mice with experimental glaucoma 3 d after laser treatment, although axonal transport of mitochondria (arrow) and preserved blood flow (open arrow) are observed. Arrowheads indicate RGC cell bodies. Time is indicated as min:s.
Yuji Takihara, Masaru Inatani, Kei Eto, Toshihiro Inoue, Alexander Kreymerman, Seiji Miyake, Shinji Ueno, Masatoshi Nagaya, Ayami Nakanishi, Keiichiro Iwao, Yoshihiro Takamura, Hirotaka Sakamoto, Keita Satoh, Mineo Kondo, Tatsuya Sakamoto, Jeffrey L. Goldberg, Junichi Nabekura, and Hidenobu Tanihara
PNAS. 2015. DOI: 10.1073/pnas.1509879112