Movie S12.

Heterochromatin dynamics in cytochalasin-D–treated LP cell. Z-projected time series of a typical H2B-EGFP labeled nucleus of NIH 3T3 cell cultured on LP micropattern after 30 min treatment with 500 nM cytochalasin-D. Blue spots represent the heterochromatin foci obtained by thresholding H2B-EGFP intensity.

Nuclear deformability and telomere dynamics are regulated by cell geometric constraints

Ekta Makhija, D. S. Jokhun, and G. V. Shivashankar

PNAS. 2015. 113:E32-E40 DOI: 10.1073/pnas.1513189113