Movie S17.
Telomere dynamics in cytochalasin-D–treated LP cell. Z-projected time series of a typical H2B-EGFP (green) and TRF1 dsRed (red) labeled nucleus of NIH 3T3 cell cultured on LP micropattern before and after 30 min of 500 nM cytochalasin-D treatment and after 30 min of washout of the drug.
Nuclear deformability and telomere dynamics are regulated by cell geometric constraints
PNAS. 2015. 113:E32-E40 DOI: 10.1073/pnas.1513189113