Movie S1.

Intravital 2-PM imaging of TMOG-GFP cells in the leptomeningeal blood stream before EAE onset. In vivo recording of TMOG-GFP cells (white circles) in T-/B-MOG (Left) and T-MOG (Right) mice at d8 p.i. Green, TMOG-GFP cells; red, Texas Red-labeled vessels. (Scale bar: 50 µm.) Time scale: h:min:s.

Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease

Anne-Christine Flach, Tanja Litke, Judith Strauss, Michael Haberl, César Cordero Gómez, Markus Reindl, Albert Saiz, Hans-Jörg Fehling, Jürgen Wienands, Francesca Odoardi, Fred Lühder, and Alexander Flügel

PNAS. 2016. DOI: 10.1073/pnas.1519608113