Movie S6.

Localization of MOG mAAb within a naive CX3CR1-EGFP cell. The animated video shows an example of a naive CX3CR1-EGFP cell that has taken up MOG mAAbs. Intravital 2-PM was performed 24 h after i.v. injection of the MOG mAAb. Red, 70 kDa Texas Red dextran for visualization of blood vessels; green, CX3CR1+ macrophages and microglia; magenta, SeTau-647–labeled MOG mAAb.

Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease

Anne-Christine Flach, Tanja Litke, Judith Strauss, Michael Haberl, César Cordero Gómez, Markus Reindl, Albert Saiz, Hans-Jörg Fehling, Jürgen Wienands, Francesca Odoardi, Fred Lühder, and Alexander Flügel

PNAS. 2016. DOI: 10.1073/pnas.1519608113