Movie S1.

Tau 623–628 is endocytosed by peritoneal B cells and macrophages. A movie constructed from the set of confocal images (63×) of peritoneal cavity cells from wild-type mice injected with 10 μg FITC-Tau 623–628 and stained with rat anti-mouse CD19 (PE), F4/80 (Alexa Fluor 647), and DAPI.

Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease

Michael Phillip Kurnellas, Eliver Eid Bou Ghosn, Jill M. Schartner, Jeanette Baker, Jesse J. Rothbard, Robert S. Negrin, Leonore A. Herzenberg, C. Garrison Fathman, Lawrence Steinman, and Jonathan B. Rothbard

PNAS. 2015. DOI: 10.1073/pnas.1521206112