Movie S2.

Caudal fin of paclitaxel-injected fish is largely denervated. Shown are axons in the distal caudal fin of an adult zebrafish on day 5 (1 d after the last injection), after four paclitaxel injections. Traces reveal widespread denervation. Axons were stained for acetylated tubulin.

Paclitaxel-induced epithelial damage and ectopic MMP-13 expression promotes neurotoxicity in zebrafish

Thomas S. Lisse, Leah J. Middleton, Adriana D. Pellegrini, Paige B. Martin, Emily L. Spaulding, Olivia Lopes, Elizabeth A. Brochu, Erin V. Carter, Ashley Waldron, and Sandra Rieger

PNAS. 2016. DOI: 10.1073/pnas.1525096113