To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie S4. Proneural wave progression in silico with reduced EGF production. The wave front exhibits a salt and pepper pattern when EGF production is reduced (ae = 0.85 and ee = ne = ed = 0). Notch-mediated lateral inhibition regulates proneural wave propagation when combined with EGF-mediated reaction diffusion Makoto Sato, Tetsuo Yasugi, Yoshiaki Minami, Takashi Miura, and Masaharu Nagayama PNAS. 2016. 113:E5153-E5162 DOI: 10.1073/pnas.1602739113 Download Original Video Browse All Videos »