Evolution of KD distribution over SELEX cycles with an initial Gaussian distribution N(−4,0.4) with added noise. The same two Monte Carlo simulations are shown as in Fig. 3 for all of the first 20 SELEX cycles.
Fabian Spill, Zohar B. Weinstein, Atena Irani Shemirani, Nga Ho, Darash Desai, and Muhammad H. Zaman
PNAS. 2016. 113:12076-12081 DOI: 10.1073/pnas.1605086113