Diffusion of αTAT1-GFP on GMPCPP-stabilized microtubules. The movie shows a microtubule in red, and fluorescent αTAT1-GFP in green. Time-lapse images are collected every 380 ms. In this movie, motile αTAT1 GFP lands on a microtubule, diffuses, and then suddenly “jumps” to a nearby microtubule, consistent with diffusion on the external surface of the microtubules.
Courtney Coombes, Ami Yamamoto, Mark McClellan, Taylor A. Reid, Melissa Plooster, G. W. Gant Luxton, Joshua Alper, Jonathon Howard, and Melissa K. Gardner
PNAS. 2016. 113:E7176-E7184 DOI: 10.1073/pnas.1605397113