Movie S2.

Visualization of the μgel network architecture in fibrin–μgel composite materials at lower fibrin concentrations. Fibrin–μgel (∼4 mg/mL and ϕ = 0.11 ULC μgels) composite networks were formed with 1.0 U/mL thrombin and imaged over time. Microgels more freely diffuse throughout the system and do not display particle–particle aggregation, nor affinity to the fibrin polymer. Individual μgel particles can be observed to jiggle around with thermal fluctuations as opposed to being physically arrested and bound to fibrin or other μgels. (Scale bar, 20 μm.)

Dynamic assembly of ultrasoft colloidal networks enables cell invasion within restrictive fibrillar polymers

Alison M. Douglas, Alexandros A. Fragkopoulos, Michelle K. Gaines, L. Andrew Lyon, Alberto Fernandez-Nieves, and Thomas H. Barker

PNAS. 2017. DOI: 10.1073/pnas.1607350114