Movie S1.

Surface representation of NPC1* with docked cholesterol. Full 360° rotation of NPC1* surface representation colored as in Fig. 1. Docked cholesterol is shown in yellow ball form.

Structure of human Niemann–Pick C1 protein

Xiaochun Li, Jiawei Wang, Elias Coutavas, Hang Shi, Qi Hao, and Günter Blobel

PNAS. 2016. DOI: 10.1073/pnas.1607795113