Movie of HeLa cells under control conditions. Time evolution of the unstained organization of HeLa cells using 63×, 1.40 NA oil-immersion objective imaged at 37 °C and 5% CO2. For this movie, each frame was collected continuously every 22 s. Interestingly, chromatin structure of the cells evolves independently and with time, even as the overall population remains steady.
Luay M. Almassalha, Greta M. Bauer, John E. Chandler, Scott Gladstein, Lusik Cherkezyan, Yolanda Stypula-Cyrus, Samuel Weinberg, Di Zhang, Peder Thusgaard Ruhoff, Hemant K. Roy, Hariharan Subramanian, Navdeep S. Chandel, Igal Szleifer, and Vadim Backman
PNAS. 2016. 113:E6372-E6381 DOI: 10.1073/pnas.1608198113