Side-by-side movie of HeLa cells under control conditions and those exposed to UV light. Time evolution of the unstained organization of HeLa cells using 63×, 1.40 N.A. oil-immersion objective for cells continuously imaged under control conditions (Left) and those exposed to UV light (Right). In both movies, each frame was collected continuously every 22 s. This side-by-side comparison allows direct visualization in the temporal behavior of chromatin structure during control conditions in comparison with that during UV exposure.
Luay M. Almassalha, Greta M. Bauer, John E. Chandler, Scott Gladstein, Lusik Cherkezyan, Yolanda Stypula-Cyrus, Samuel Weinberg, Di Zhang, Peder Thusgaard Ruhoff, Hemant K. Roy, Hariharan Subramanian, Navdeep S. Chandel, Igal Szleifer, and Vadim Backman
PNAS. 2016. 113:E6372-E6381 DOI: 10.1073/pnas.1608198113