Tridimensional structure of subcapsular sinus traversing conduits. Confocal images of a sheep LN assembled into a 3D rendering, showing one of the conduits crossing the SCS. The conduit is delimited by a basal membrane of perlecan (red) and enveloped by JAM-A+ endothelial cells (green); nuclei were stained with DAPI (blue).
Eleonora Melzi, Marco Caporale, Mara Rocchi, Verónica Martín, Virginia Gamino, Andrea di Provvido, Giuseppe Marruchella, Gary Entrican, Noemí Sevilla, and Massimo Palmarini
PNAS. 2016. DOI: 10.1073/pnas.1610012113