Movie S1.

YFP–ForG-N localizes to macropinosomes (refers to Fig. 1B). Time-lapse recordings of a cell coexpressing LifeAct-mRFP and YFP–ForG-N acquired by confocal microscopy. (Right) Merged channels reveal colocalization of F-actin and ForG at macropinosomes. Time is minutes and seconds. (Scale bar: 5 μm.)

A Diaphanous-related formin links Ras signaling directly to actin assembly in macropinocytosis and phagocytosis

Alexander Junemann, Vedrana Filić, Moritz Winterhoff, Benjamin Nordholz, Christof Litschko, Helena Schwellenbach, Till Stephan, Igor Weber, and Jan Faix

PNAS. 2016. DOI: 10.1073/pnas.1611024113