Movie S3.

Random migration of forG-KO cells is not impaired compared with WT cells. Time-lapse recordings of WT and forG-KO cells acquired by phase-contrast microscopy. Note the extensive ruffles and markedly exaggerated pseudopodia-like membrane extension formed by forG-KO cells, which differs considerably from WT cells mainly forming cups. Time is minutes and seconds. (Scale bar: 10 μm.)