Movie S4.

Evolution of tissue PSA distribution on an axial section at the midgland. This simulation was run with the same parameters as the one depicted in Fig. 4, the total time of simulation being 1 y. The section depicted is at z = 25.5 mm, with the origin of the coordinate z set at the prostate base. The white line is the contour of the tumor.

Tissue-scale, personalized modeling and simulation of prostate cancer growth

Guillermo Lorenzo, Michael A. Scott, Kevin Tew, Thomas J. R. Hughes, Yongjie Jessica Zhang, Lei Liu, Guillermo Vilanova, and Hector Gomez

PNAS. 2016. DOI: 10.1073/pnas.1615791113