Movie S2.

MD simulation of the E form of ERp44 with Cys29 protonated (related to Fig. 4 B and C). The interactions formed between the a domain (light green) and the shielding segment of the C tail (magenta) are highlighted (related to Fig. 4 B and C).

Structural basis of pH-dependent client binding by ERp44, a key regulator of protein secretion at the ER–Golgi interface

Satoshi Watanabe, Manami Harayama, Shingo Kanemura, Roberto Sitia, and Kenji Inaba

PNAS. 2017. DOI: 10.1073/pnas.1621426114

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