Movie S1.

Trajectory of Tpm movement on the surface of F-actin. Movie starts from the transition of the c-blocked (blue) into the c-closed state (green), followed by transition of the c-closed (green) into the c-open (magenta) state. Finally, transition of c-open state into the myosin state (cyan) completes the Tpm swing on F-actin.

Ca2+-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy

Cristina Risi, Jamie Eisner, Betty Belknap, David H. Heeley, Howard D. White, Gunnar F. Schröder, and Vitold E. Galkin

PNAS. 2017. 114:6782-6787 DOI: 10.1073/pnas.1700868114