Movie S1.

Related to Fig. 1G. Nonpolarized, Lat B-treated WT cells expressing RBD-GFP (green) were stimulated with 10 μM cAMP (red).

GPCR-controlled membrane recruitment of negative regulator C2GAP1 locally inhibits Ras signaling for adaptation and long-range chemotaxis

Xuehua Xu, Xi Wen, Douwe M. Veltman, Ineke Keizer-Gunnink, Henderikus Pots, Arjan Kortholt, and Tian Jin

PNAS. 2017. 114:E10092-E10101 DOI: 10.1073/pnas.1703208114