To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie S4. Related to Fig. 3C. Nonpolarized, Lat B-treated c2gapA− cells expressing PHcrac-GFP (green) were stimulated with 10 nM, 100 nM, 1 μM, or 10 μM Sp-cAMP (red), from Left to Right, respectively. GPCR-controlled membrane recruitment of negative regulator C2GAP1 locally inhibits Ras signaling for adaptation and long-range chemotaxis Xuehua Xu, Xi Wen, Douwe M. Veltman, Ineke Keizer-Gunnink, Henderikus Pots, Arjan Kortholt, and Tian Jin PNAS. 2017. 114:E10092-E10101 DOI: 10.1073/pnas.1703208114 Download Original Video Browse All Videos »