Movie S1.

Morphing of the trimer from the closed to open conformation as viewed along the viral membrane. Interpolation between the RBD “in” conformation and the RBD “out” conformation. RBDs are colored green and NTDs are colored blue. The rest of the trimer is colored gray.

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen

Jesper Pallesen, Nianshuang Wang, Kizzmekia S. Corbett, Daniel Wrapp, Robert N. Kirchdoerfer, Hannah L. Turner, Christopher A. Cottrell, Michelle M. Becker, Lingshu Wang, Wei Shi, Wing-Pui Kong, Erica L. Andres, Arminja N. Kettenbach, Mark R. Denison, James D. Chappell, Barney S. Graham, Andrew B. Ward, and Jason S. McLellan

PNAS. 2017. 114:E7348-E7357 DOI: 10.1073/pnas.1707304114

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