To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie S2. Time-lapse RICM imaging showing human platelet spreading on 0.1% biotinylated lipid SLB decorated with fibrinogen. No significant cell adhesion and cell spreading were observed. (Scale bar: 10 μm.) Platelet integrins exhibit anisotropic mechanosensing and harness piconewton forces to mediate platelet aggregation Yun Zhang, Yongzhi Qiu, Aaron T. Blanchard, Yuan Chang, Josh M. Brockman, Victor Pui-Yan Ma, Wilbur A. Lam, and Khalid Salaita PNAS. 2017. 115:325-330 DOI: 10.1073/pnas.1710828115 Download Original Video Browse All Videos »