To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie S8. Time-lapse video showing the loss of platelet tension upon treatment of MLCK inhibitor (ML-7). Two channels were recorded: RICM (Left) and 4.7-pN tension signal (Right, TRITC). (Scale bar: 10 μm.) Platelet integrins exhibit anisotropic mechanosensing and harness piconewton forces to mediate platelet aggregation Yun Zhang, Yongzhi Qiu, Aaron T. Blanchard, Yuan Chang, Josh M. Brockman, Victor Pui-Yan Ma, Wilbur A. Lam, and Khalid Salaita PNAS. 2017. 115:325-330 DOI: 10.1073/pnas.1710828115 Download Original Video Browse All Videos »