Representative example of a Wdr47tm1a/tm1a primary hippocampal neuron at 2 d in vitro recorded live in culture at 30-min intervals for 24 h, displaying slow, aberrant, and much less dynamic microtubules at the growth cone, which is visibly smaller.
Meghna Kannan, Efil Bayam, Christel Wagner, Bruno Rinaldi, Perrine F. Kretz, Peggy Tilly, Marna Roos, Lara McGillewie, Séverine Bär, Shilpi Minocha, Claire Chevalier, Chrystelle Po, None None, Jamel Chelly, Jean-Louis Mandel, Renato Borgatti, Amélie Piton, Craig Kinnear, Ben Loos, David J. Adams, Yann Hérault, Stephan C. Collins, Sylvie Friant, Juliette D. Godin, and Binnaz Yalcin
PNAS. 2017. 114:E9308-E9317 DOI: 10.1073/pnas.1713625114