Movie S1.
CHD4 is required for ventricular systolic function at E10.5. Chd4flox/flox embryo shows strong, frequent atrial and ventricular contractions measured by blood flow velocity using PW Doppler echocardiography at the atrioventricular canal.
CHD4 and the NuRD complex directly control cardiac sarcomere formation
PNAS. 2018. 115:6727-6732 DOI: 10.1073/pnas.1722219115